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The Chronic Cough Enigma: How to recognize, diagnose and treat neurogenic and reflux related cough

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Pertussis, or whooping cough, is a severe and debilitating cough illness that can last for weeks to months. A common misconception is that pertussis is a disease of infants and children. Active pertussis infection in adolescents and adults is an underrecognized cause of chronic cough. One investigation found a 21% incidence of pertussis in a group of patients with a cough duration of 2 weeks to 3 months. In recent years, the incidence of pertussis has increased, most likely due to a combination of waning immunity and increased detection of the illness. Patients experience periodic episodes of violent coughing, and post-tussive emesis is common. The inspiratory whooping sound typical in children is generally not heard in adults., Diagnosis of cough due to pertussis may be aided by demonstration of positive polymerase chain reaction in nasopharyngeal secretions in the acute setting and serum immunoglobulin G analysis later on in the course.

Pertussis, or whooping cough, is a severe and debilitating cough illness that can last for weeks to months. A common misconception is that pertussis is a disease of infants and children. Active pertussis infection in adolescents and adults is an underrecognized cause of chronic cough. One investigation found a 21% incidence of pertussis in a group of patients with a cough duration of 2 weeks to 3 months. In recent years, the incidence of pertussis has increased, most likely due to a combination of waning immunity and increased detection of the illness. Patients experience periodic episodes of violent coughing, and post-tussive emesis is common. The inspiratory whooping sound typical in children is generally not heard in adults., Diagnosis of cough due to pertussis may be aided by demonstration of positive polymerase chain reaction in nasopharyngeal secretions in the acute setting and serum immunoglobulin G analysis later on in the course.

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Diagnosis - Chronic cough - Mayo Clinic

Clinicians must keep in mind that there are broader differential diagnoses of cough in all patients and cough may be the initial presenting symptom of a serious disease, such as tuberculosis, lung cancer, and heart disease.